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丹參酮IIA

分析標(biāo)準(zhǔn)品,HPLC≥98%

Tanshinone IIA

CAS號：568-72-9

分子式：C19H18O3

分子量：294.34

MDL：MFCD00238692

產(chǎn)品介紹

熔點：205-207℃

沸點：480.7℃ at 760 mmHg

外觀：桔紅色針狀結(jié)晶

溶解性：按照順序添加:5%  DMSO+30%  PEG  300+2%  Tween  80+ddH2O。此方法可以溶解0.2mg/ml。丹參酮IIA溶液狀態(tài)下不穩(wěn)定，需要現(xiàn)配現(xiàn)用，不能儲備液形式儲存。

儲存條件：2-8℃

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(106篇)

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90. [IF=3.5] Yuanjie Wu et al."Tanshinone IIA Combined With Rutin and Squalene Improves Hyperlipidemia to Alleviate Atherosclerosis in New Zealand Rabbits Through Upregulation of the SREBP2/LDLR Pathway."JOURNAL OF FOOD BIOCHEMISTRY.2025 Apr;2025(1):8349248

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83. [IF=2.8] Fang Liang et al."Therapeutic effects of Tanshinone IIA and Tetramethylpyrazine nanoemulsions on cognitive impairment and neuronal damage in Alzheimer’s disease rat models."JOURNAL OF PHARMACY AND PHARMACOLOGY.2024 Jun;:

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81. [IF=2.6] Cheng Shao et al."Local Application of Tanshinone IIA protects mesenchymal stem cells from apoptosis and promotes fracture healing in ovariectomized mice."Journal of Orthopaedic Surgery and Research".2024 Dec;19(1):1-12

80. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal

79. [IF=7.9] Mingyu Wu et al."Tanshinone IIA positively regulates the Keap1-Nrf2 system to alleviate pulmonary fibrosis via the sestrin2-sqstm1 signaling axis-mediated autophagy."PHYTOMEDICINE".2024 Apr;:155620

78. [IF=10.2] Guo Hong et al."Homologous-magnetic dual-targeted metal-organic framework to improve the Anti-hepatocellular carcinoma efficacy of PD-1 inhibitor."JOURNAL OF NANOBIOTECHNOLOGY".2024 Dec;22(1):1-20

77. [IF=1.8] Meile Ma et al."Tanshinone IIA Regulates Synaptic Plasticity in Mg2+-Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway."Journal of Integrative Neuroscience".2024 Mar;23(3):61

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73. [IF=10.7] Baixi Shan et al."Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-13C5]-glutamine metabolic flux analysis."Journal of Advanced Research".2024 May;:

72. [IF=4.7] Xu Zhang et al."Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection."FISH & SHELLFISH IMMUNOLOGY.2024 Jan;144:109284

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63. [IF=3.97] Xin Zhang et al."Nano-encapsulated tanshinone IIA in PLGA-PEG-COOH inhibits apoptosis and inflammation in cerebral ischemia/reperfusion injury."Green Processing and Synthesis.2023 Jan;12(1):

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51. [IF=2.629] Zhu Yinxing et al.PEI-PEG-Coated Mesoporous Silica Nanoparticles Enhance the Antitumor Activity of Tanshinone IIA and Serve as a Gene Transfer Vector.Evid-Based Compl Alt. 2021;2021:6756763

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39. [IF=4.411] Yuanyuan Li et al."Quantitative Determination and Validation of Four Ketones in Salvia miltiorrhiza Bunge Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy."Molecules. 2020 Jan;25(9):2043

38. [IF=5.793] Ding  Bo et al."Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro."J Neuroinflamm. 2020 Dec;17(1):1-17

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33. [IF=1.863] Ligang Jie et al."Tanshinone IIA induces apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis via blockade of the cell cycle in the G2/M phase and a mitochondrial pathway."Biological & Pharmaceutical Bulletin. 2014 Jun 11

32. [IF=7.514] Tiehua Zhang et al."In vitro and in silico perspectives on estrogenicity of tanshinones from Salvia miltiorrhiza."Food Chem. 2019 Jan;270:281

31.  Miao-Juan Shi, Xiu-Li Yan, Ben-Sheng Dong, Wen-Na Yang, Shi-Bing Su, Hui Zhang,

A network pharmacology approach to investigating the mechanism of Tanshinone IIA for the treatment of liver fibrosis,

Journal of Ethnopharmacology,

Volume 253,

2020,

112689,

IS

30.  Li, Zhe, et al. "Folic acid modified lipid-bilayer coated mesoporous silica nanoparticles co-loading paclitaxel and tanshinone IIA for the treatment of acute promyelocytic leukemia." International Journal of Pharmaceutics 586 (2020): 119576.https:##doi.org

29.  Lu?btow, Michael M., et al. "Like dissolves like? A comprehensive evaluation of partial solubility parameters to predict polymer–drug compatibility in ultrahigh drug-loaded polymer micelles." Biomacromolecules 20.8 (2019): 3041-3056.https:##doi.org/10.1021

28.  Yang, Runyu, et al. "Limonin ameliorates acetaminophen-induced hepatotoxicity by activating Nrf2 antioxidative pathway and inhibiting NF-κB inflammatory response via upregulating Sirt1." Phytomedicine 69 (2020): 153211.https:##doi.org/10.1016/j.phymed.2020

27.  Ding, B., Lin, C., Liu, Q. et al. Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro. J Neuroinflammation 17, 302 (2020). https:##doi.org/10.1186/s12974-020-01981-4

26.  Li, Zhe, et al. "Biotinylated-lipid bilayer coated mesoporous silica nanoparticles for improving the bioavailability and anti-leukaemia activity of Tanshinone IIA." Artificial cells, nanomedicine, and biotechnology 46.sup1 (2018): 578-587.https:##doi.org/1

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